The webpage is not working since JavaScript is not enabled. Most likely, you are viewing using Dropbox website or another limited browser environment.
LogD Calculator
Ligand Efficiency Calculator
Pharmacokinetic Simulator
clogP
Acid/Neutral/Base
pKa
pH
% ionisation
logD
Acid
Neutral
Base
IC
50
(nM)
Heavy Atom Count
(HAC)
clogP
Ligand
Efficiency
(LE)
Ligand Lipophilic
Efficiency
(LLE)
[No canvas support]
Primary Pharmacology (IC
50
) nM
Multiple of IC
50
(set at x3)
MW
(g/mol)
Vd
(L/Kg)
Cl
(mL/min/Kg)
Dose interval (h)
Number
of doses
Absorption Rate Constant
(h
-1
)
8
12
24
1
2
3
4
5
6
7
0.10
1.00
2.00
3.00
4.00
5.00
6.00
7.00
8.00
9.00
10.00
Subject Weight (Kg) (Set at 70)
Absorption%
(set at 100)
PPB%
(set at 90)
Dose Size
(mg)
F%
Half-life
(h)
C
max
(free)
(nM)
t
max
(h)
Calculate
Reset
Print